Can you cut toprol xl in half

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This content does not have an English version. This content does not have an Arabic version. See more conditions. Drugs and Supplements Metoprolol Oral Route. The tablets come from the manufacturer "scored" down the middle to aide in spitting. As stated, Toprol XL is one of the few extended release medications that is safe to cut in half. This is due to the extended release mechanism of the tablets. The actual active ingredient in Toprol XL tablets are encapsulated in "micropellets" that are evenly distributed throughout the tablet, as shown in the below image:.

Source: Toprol XL Information. Once these pellets reach the digestive tract, they slowly disintegrate and deliver the medication at a controlled rate for a 24 hour effect. As the micropellets are evenly distributed in Toprol XL tablets and aren't disrupted when a tablet is cut, Toprol XL is safe to split. In fact, the tablets come scored from the manufacturer to ease splitting. He has been featured in numerous publications including the Huffington Post as well as a variety of health and pharmacy-related blogs.

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Since all commercial metoprolol succinate extended release tablets are scored, they are deemed suitable for splitting. The present study was aimed at utilizing an innovative technology to determine the dose uniformity for split tablets. Four marketed drug products consisting of innovator and generics were evaluated for effect of splitting on weight, assay and content uniformity.